Calculation of drug dose which produces 'all-or-nothing' response in 50% of subjects (effective dose 50) using probits
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چکیده
منابع مشابه
Abstract 50. Migraine Surgery Outcomes: An All or Nothing Phenomenon?
PURPOSE: Head and neck melanoma is associated with a high false negative sentinel lymph node biopsy (SLNB) rate. Our group previously demonstrated the combination of radiotracer and ICG SPY Elite navigation system was feasible and more sensitive compared to standard vital dye and radioactive tracer for SLNB. The goal of this report was to analyze our experiences utilizing ICG fluorescence with ...
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Nowadays, in order to improve the accuracy of treatment in radiation therapy, there are many attempts to use magnetic resonance imaging (MRI) due to the advantages of excellent soft tissue contrast and ultra-fast pulse sequences. On the other hand, carbon-ion radiation therapy is developing rapidly due to the benefits of greater relative biological effectiveness (RBE) and the application in the...
متن کاملCalculation of wedged dose distributions using an analytical method
Introduction: Wedge filters are used in radiotherapy to modify photon beam and improve dose uniformity in the target volume. Determination of wedge dose distribution is important to improve treatment planning accuracy. The utilization of treatment planning software to obtain dose distribution is not always available. In this work an analytical model has been developed to calcu...
متن کاملDetermination of the 50% human infectious dose for Norwalk virus.
BACKGROUND Noroviruses are the most common cause of gastroenteritis in the United States. An understanding of the infectious dose of these viruses is important for risk assessment studies. METHODS Healthy adults were enrolled in a randomized, double-blind, placebo-controlled evaluation of different dosages of Norwalk virus. Eligible subjects were monitored for clinical gastroenteritis, and ...
متن کاملDose distribution evaluation of various dose calculation algorithms in inhomogeneous media
Background: Dose calculation algorithms play a very important role in predicting the explicit dose distribution. We evaluated the percent depth dose (PDD), lateral depth dose profile, and surface dose volume histogram in inhomogeneous media using calculation algorithms and inhomogeneity correction methods. Materials and Methods: The homogeneous and inhomogeneous virtual slab phantoms used in th...
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ژورنال
عنوان ژورنال: Racionalna terapija
سال: 2018
ISSN: 1821-0538,2217-8627
DOI: 10.5937/racter10-16880